Video 4. Comparison of preventive (blue lines and shading) and post-diagnostic (red lines, hatched) interventions.
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DOI: 10.7554/eLife.06266.021
Tumours are treated at M0 = 106 cells. (A) The median (thick line) and 90% confidence intervals (shaded areas with dashed boundaries) for the distribution of times to relapse for treatment failures. (B) and (C) Arbitrary samples of the distribution of detection times for preventive and post-diagnostic interventions, respectively. The colour-code indicates the mean number of accumulated drivers over a period of 1 year. The rectangles on the top of B and on the bottom of C show the fifth and 95th percentiles, the blue circle indicates the median, and the red line is the mean. Parameters as in Table 1.