Video 5. Comparison of preventive (blue lines and shading) and post-diagnostic (red lines, hatched) interventions.
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DOI: 10.7554/eLife.06266.022
Tumours are treated at M0 = 104 cells. (A) The median (thick line) and 90% confidence intervals (shaded areas with dashed boundaries) for the distribution of times to relapse for treatment failures. (B) and (C) Arbitrary samples of the distribution of detection times for preventive and post-diagnostic interventions, respectively. The colour-code indicates the mean number of accumulated drivers over a period of 1 year. The rectangles at the top of B and the bottom of C shows the fifth and 95th percentiles, the blue circle indicates the median, and the red line is the mean. Parameters as in Table 1.