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. 2015 Jul 29;10:4763–4781. doi: 10.2147/IJN.S75101

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© 2015 Korang-Yeboah et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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PCL/MD nanocarrier uptake and internalization enhances bioavailability of encapsulated molecule.

Notes: (A) Flow cytometry histograms of LNCaP, DU145, and PC3 after 2 hours of treatment with 25 μg/mL of fluorescent-labeled PCL/MD nanocarrier (red), free fluorescent dye (yellow), and untreated cell line (blue) and medium in which an equivalent amount of nanocarrier has been previously suspended (black). (B) Cellular internalization of PCL/MD in LNCaP, DU145, and PC3. Fluorescence microscopic images of uptake taken (after 2 hours) with a Zeiss ApoTome microscope with an Axiom Cam version 4.5 imaging system at 40× magnification.

Abbreviations: PCL, polycaprolactone; MD, maltodextrin.