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Effect of pharmacological inhibitors on PCL/MD uptake in PC3, DU145, and LNCaP.
Notes: The role of endogenous cholesterol, macropinocytosis, clathrin, and clathrin-independent mechanisms was determined by prior treatment with methyl-β-cyclodextrin, amiloride, nystatin, and chlorpromazine respectively.
Abbreviations: PCL, polycaprolactone; MD, maltodextrin; Pos cont, positive control; MβCD, methyl-β-cyclodextrin; CPZ, chlorpromazine; Neg cont, negative control.
