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. 2015 Jul 28;10:4747–4761. doi: 10.2147/IJN.S82940

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© 2015 Liu et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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(A) Cellular uptake of rhodamine-labeled PMSG or TMSG in MDA-MB-231 cells and then quantization of mean FL intensity by flow cytometry. (B) Cellular association of rhodamine-labeled TMSG in the presence of different endocytosis inhibitors in MDA-MB-231 cells.

Notes: The geometric mean of the fluorescence for the cells treated with rhodamine-labeled TMSG without any inhibitors was defined as 100% (n=3). ***P<0.001, **P<0.01, *P<0.05, and NS, not statistically significant.

Abbreviations: FL, fluorescence; PMSG, polyethylene glycol-modified mesoporous silica-coated gold nanorods; TMSG, tLyp-1 peptide-functionalized PMSG; min, minutes; M-β-CD, methyl-β-cyclodextrin; MDA-MB-231cells, MD Anderson-metastatic breast-231 cells.