Table 1.

Host-restricted loss-of-function models for vascular normalization

Target gene	Cell type	Model	Reference
Rgs5	General	RIP1-Tag5 pancreatic tumor	Hamzah et al. [17]
Ang2	General	s.c. lung tumor and melanoma	Nasarre et al. [20]
PlGF	General	Skin tumor, liver tumor, RIP1-Tag2 pancreatic tumor, s.c. mammary tumor, fibrosarcoma, Panc02 pancreatic tumor	Van de Veiri et al. [21], Rolny et al. [25]
R-Ras	General	s.c. lung tumor, melanoma, prostate tumor	Sawada et al. [18]
Siah2	General	PyMT mammary tumor	Wong et el. [23]
PHD2	Endothelial	Pancreatic tumor, s.c. lung tumor, and melanoma	Mazzone et al. [13]
FAK	Endothelial	Glioma	Lee et al. [6]
Sox17	Endothelial	s.c. lung tumor and melanoma	Yang et al. [14]
VEGF-A	Myeloid cell	MMTV-PyVT, s.c. lung tumor	Stockmann et al. [24]