Table 1.
Demographic and Clinical Characteristics by Assignment Group
| Characteristic | NSAID Group | Non-NSAID Group | P Value |
|---|---|---|---|
| Total, No. (%) of patients | 3158 (24.1) | 9924 (75.9) | NA |
| Age, mean (SD), y | 54.9 (15.4) | 59.1 (15.8) | <.001 |
| Female sex, No. (%) | 1926 (61.0) | 6014 (60.6) | .66 |
| Charlson Comorbidity Index, No. (%) | |||
| 0 | 1631 (51.7) | 4387 (44.2) | <.001 |
| 1 | 478 (15.1) | 1832 (18.5) | |
| 2 | 557 (17.6) | 1795 (18.1) | |
| ≥3 | 492 (15.6) | 1910 (19.2) | |
| Cardiac risk index, No. (%) | |||
| 0 | 2874 (91.0) | 8305 (83.7) | <.001 |
| 1 | 227 (7.2) | 1241 (12.5) | |
| 2 | 54 (1.7) | 328 (3.3) | |
| ≥3 | 3 (0.1) | 50 (0.5) | |
| Albumin level <3 g/dL, No. (%) | 152 (4.8) | 685 (6.9) | <.001 |
| Admission priority, No. (%) | |||
| Emergency/urgent | 300 (9.5) | 1280 (12.9) | <.001 |
| Elective | 2858 (90.5) | 8644 (87.1) | <.001 |
| Procedure type, No. (%) | |||
| Bariatric | 656 (20.8) | 2562 (25.8) | <.001 |
| Colectomy | |||
| Nonelective | 308 (9.8) | 1313 (13.2) | <.001 |
| Elective | 2194 (69.5) | 6049 (61.0) | <.001 |
| Anastomosis tested, No. (%) | 1740 (55.1) | 5567 (56.1) | .34 |
| Diverting ostomy, No. (%)a | 319 (12.7) | 850 (11.5) | .29 |
| Open procedure or conversion to open procedure, No. (%) | 1794 (56.8) | 5706 (57.5) | .47 |
| Time to oral intake, mean (SD), da | 3.6 (3.0) | 4.7 (3.7) | <.001 |
| Epidural, No. (%) | 666 (21.1) | 1856 (18.7) | .003 |
| Patient-controlled analgesia, No. (%) | 2564 (81.2) | 8296 (83.6) | .002 |
Abbreviations: NA, not applicable; NSAID, nonsteroidal anti-inflammatory drug.
SI conversion factor: To convert albumin to grams per liter, multiply by 10.
a
Includes patients undergoing colorectal procedures only.