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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: JAMA Surg. 2015 Mar 1;150(3):223–228. doi: 10.1001/jamasurg.2014.2239

Table 2.

Risk for Anastomotic Leak Among All Patients

Variable OR (95% CI)
Unadjusted Adjusted
Age 1.00 (1.00–1.01) 0.99 (0.99–1.00)
Male sex 1.56 (1.27–1.93) 1.50 (1.27–1.75)
Charlson Comorbidity Index
 0 1 [Reference] 1 [Reference]
 1 0.74 (0.60–0.93) 0.91 (0.69–1.21)
 2 0.93 (0.65–1.34) 0.99 (0.60–1.63)
 ≥3 1.05 (0.82–1.34) 0.97 (0.63–1.52)
BMI ≥30 0.74 (0.57–0.96) 1.04 (0.71–1.41)
Albumin level <3 g/dL 2.73 (2.01–3.70) 2.20 (1.63–2.96)
Procedure type
 Bariatric 1 [Reference] 1 [Reference]
 Colorectal 2.01 (1.08–3.72) 1.20 (0.67–2.11)
 Nonelective colorectal 4.04 (2.17–7.47) 1.44 (0.97–3.04)
Anastomosis tested 0.76 (0.59–0.97) 1.10 (0.90–1.35)
Postoperative NSAID administration 1.15 (0.92–1.42) 1.24 (1.01–1.56)
Epidural 1.07 (0.70–1.63) 1.05 (0.74–1.50)
Patient-controlled analgesia 0.94 (0.60–1.46) 0.95 (0.60–1.50)

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); NSAID, nonsteroidal anti-inflammatory drug; OR, odds ratio.

SI conversion factor: To convert albumin to grams per liter, multiply by 10.