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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: JAMA Surg. 2015 Mar 1;150(3):223–228. doi: 10.1001/jamasurg.2014.2239

Table 3.

Risk for Anastomotic Leak Among 1621 Patients Undergoing Nonelective Colorectal Procedures

Variable OR (95% CI)
Unadjusted Adjusted
Age 1.00 (0.99–1.01) 0.98 (0.97–1.00)
Male sex 1.32 (0.87–2.00) 1.42 (0.88–2.30)
Charlson Comorbidity Index
 0 1 [Reference] 1 [Reference]
 1 1.35 (0.82–2.24) 1.43 (0.82–2.51)
 2 1.04 (0.70–1.55) 1.61 (0.86–2.99)
 ≥3 0.80 (0.55–1.17) 1.15 (0.59–2.23)
Cancer diagnosis 0.73 (0.51–1.05) 0.82 (0.43–1.55)
BMI ≥30 1.19 (0.93–1.54) 0.97 (0.67–1.41)
Albumin level <3 g/dL 1.61 (1.11–2.32) 1.74 (1.22–2.47)
Open procedure 1.53 (0.91–2.58) 1.57 (0.81–3.01)
Anastomosis tested 0.92 (0.66–1.28) 1.03 (0.63–1.69)
Protective ostomy 1.51 (0.77–2.25) 0.89 (0.76–1.02)
Postoperative NSAID administration 1.57 (1.08–2.27) 1.70 (1.11–2.68)
Epidural 0.78 (0.42–1.45) 0.68 (0.32–1.45)
Patient-controlled analgesia 0.70 (0.43–1.14) 0.54 (0.31–0.95)

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); NSAID, nonsteroidal anti-inflammatory drug; OR, odds ratio.

SI conversion factor: To convert albumin to grams per liter, multiply by 10.