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. 2015 Jul 30;9:4105–4113. doi: 10.2147/DDDT.S89077

Figure 4.

Figure 4

Glutam-1-yl celecoxib-dextran ester (G1CD) does not affect the serum level of 6-ketoprostaglandin F (6-keto-PGF).

Notes: (A) Celecoxib in the blood was analyzed by HPLC at appropriate time intervals after oral administration of G1CD or celecoxib. The data represent mean ± SEM (n=5). (B) 6-keto-PGF in the blood was analyzed using an ELISA kit at appropriate time intervals after oral administration of G1CD or celecoxib. The data represent the mean ± SEM (n=5). *P<0.05 vs control; **P>0.05 vs control; #P<0.05 vs celecoxib; ##P>0.05 vs celecoxib at each time point.

Abbreviations: HPLC, high-performance liquid chromatography; ELISA, enzyme-linked immunosorbent assay.