TABLE 2.

Overall and disease-specific survival rates for infiltrating salivary duct carcinoma cases reported in Surveillance, Epidemiology, and End Results database.

			DSS rate (%)*
Factor	Median OS, mo	Median DSS, mo	1 y	2 y	3 y	5 y	10 y
All salivary duct carcinoma (n = 228)	79	>120†	91	82	78	64	56
Age at diagnosis, y
≤50 (n = 33)	>120†	>120†	100	94	94	86	78
51–60 (n = 45)	58	>120†	95	85	77	54	54
61–70 (n = 65)	50	59	85	79	72	49	35
>70 (n = 85)	74	>120†	89	78	76	70	62
	p < .001‡	p = .01‡
Sex
Male (n = 166)	80	>120†	92	84	79	64	56
Female (n = 62)	80	>120†	86	79	77	62	58
	p = .90‡	p = .77‡
Primary site
Parotid only (n = 163)	78	>120†	91	82	77	62	58
Submandibular only (n = 33)	45	58	94	80	76	48	35
	p = .57‡	p = .20‡
Tumor grade
Well or moderately differentiated (n = 29)	>120†	>120†	89	89	89	89	71
Poorly or undifferentiated (n = 120)	47	56	90	79	73	47	44
	p value = .02‡	p value = .02‡
Overall stage
I or II (n = 78)	>120†	>120†	96	91	90	84	76
III (n = 49)	86	>120†	96	88	86	67	67
IV-A or IV-B (n = 85)	40	46	90	76	69	45	40
IV-C (n = 13)	15	17	54	46	35	12	0
	p < .001‡	p < .001‡
SEER historic stage
Localized (n = 83)	>120†	>120†	96	92	91	86	78
Regional (n = 98)	51	>120†	93	84	76	54	51
Distant (n = 44)	38	40	76	60	56	29	20
	p < .001‡	p < .001‡
Lymph node status
Negative (n = 114)	>120†	>120†	95	90	88	80	73
Positive (n = 111)	44	48	87	74	68	44	38
	p < .001‡	p < .001‡
Tumor size
≤2 cm (n = 85)	84	>120†	94	90	86	66	55
>2–3 cm (n = 50)	95	>120†	96	88	79	75	75
>3 cm (n = 58)	43	46	83	64	64	47	42
	p value = .03‡	p value = .006‡

Abbreviations: OS, overall survival; DSS, disease-specific survival; SEER, Surveillance, Epidemiology, and End Results.

^*Absolute survival rates.

^†Median not reached at 10-year follow-up.

^‡Based on log-rank test.