Table 2.

Genotype and allele distributions of GRK6/ARRB2 in the SZ cases and controls

SNP	Subjects	Genotype (%)			χ2-value	P-value	Allele (%)		χ2-value	P-value
GRK6
		TT	TC	CC			T	C
rs883576	Controls (N=330)	11 (3)	79 (24)	240 (73)	0.534	0.77	101 (15)	559 (85)	0.284	0.59
	SZ (N=333)	8 (2)	79 (24)	246 (74)			95 (14)	571 (86)
		TT	TC	CC			T	C
rs867755	Controls (N=330)	13 (4)	72 (22)	245 (74)	1.317	0.52	98 (15)	562 (85)	0.289	0.59
	SZ (N=333)	8 (2)	76 (23)	249 (75)			92 (14)	574 (86)
		GG	GA	AA			G	A
rs2287694	Controls (N=330)	62 (19)	169 (51)	99 (30)	1.717	0.42	293 (44)	367 (56)	0.709	0.40
	SZ (N=333)	76 (23)	159 (48)	98 (29)			311 (47)	355 (53)
		CC	CG	GG			C	G
rs1130857	Controls (N=330)	0 (0)	93 (28)	237 (72)	0.060	0.81	93 (14)	567 (86)	0.051	0.82
	SZ (N=333)	0 (0)	91 (27)	242 (73)			91 (14)	575 (86)
		GG	GA	AA			G	A
rs335435	Controls (N=330)	11 (3)	190 (58)	129 (39)	3.203	0.20	212 (32)	448 (68)	1.776	0.18
	SZ (N=333)	12 (4)	213 (64)	108 (32)			237 (36)	429 (64)
ARRB2
		AA	AG	GG			A	G
rs2271167	Controls (N=330)	3 (1)	61 (18)	266 (81)	3.118	0.21	67 (10)	593 (90)	0.180	0.67
	SZ (N=333)	7 (2)	49 (15)	277 (83)			63 (9)	603 (91)
		CC	CT	TT			T	C
rs1045280	Controls (N=330)	4 (1)	74 (22)	252 (77)	4.256	0.12	82 (12)	578 (88)	0.053	0.82
	SZ (N=333)	10 (3)	60 (18)	263 (79)			80 (12)	586 (88)
		AA	AG	GG			A	G
rs3786047	Controls (N=330)	3 (1)	73 (22)	254 (77)	4.768	0.09	79 (12)	581 (88)	0.162	0.69
	SZ (N=333)	9 (3)	57 (17)	267 (80)			75 (11)	591 (89)

Abbreviations: SNP, single nucleotide polymorphism; SZ, schizophrenia.