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. 2015 Aug 4;10(8):e0133020. doi: 10.1371/journal.pone.0133020

Fig 1. Pedigree and genotype–phenotype relationship of the family.

Fig 1

The pedigree of individuals with cancer is represented by black circles (lung adenocarcinoma) and a gridded circle (endometrial cancer). A line through a symbol indicates that the person is deceased. The mutation status of WRN, DICER1, and ELAC2 is presented in each individual who underwent multiplex genetic sequencing. A plus sign represents a mutant type, and a minus sign represents a wild type.