Table 5. Gene Expression Profile of Middle-Aged Sham and CCI DRG at Day 7.

Gene	MS Mean	SD	n	MCCI Mean	SD	n	Fold MCCI/MS	p value
ATF3	32.2	31.2	5	69.8	53.7	6	2.17	0.5260
CCL2	17.4	2.51	9	34.7	7.14	10	1.99	0.0001
CD2	1.19	0.29	9	1.38	0.47	10	1.16	0.8640
CD3E	0.80	0.29	5	0.81	0.30	6	1.01	0.9999
CD45	7.69	2.44	5	6.89	1.95	6	0.90	0.8712
CD68	5.59	1.32	9	6.63	1.56	10	1.19	0.6886
GFAP	18.5	6.71	5	25.0	10.5	6	1.35	0.6285
IFN-γ	0.30	0.13	9	0.36	0.24	10	1.20	0.9351
IL10	0.54	0.24	5	0.57	0.33	6	1.06	0.9999
IL17a	0.82	0.24	4	1.17	0.39	4	1.43	0.7730
IL1β	0.28	0.10	9	0.36	0.08	10	1.29	0.3928
IL6	0.73	0.26	9	5.36	2.85	10	7.34	0.0001
TGFβ1	8.05	1.88	5	7.34	1.25	6	0.91	0.8293
TNFα	1.59	0.28	4	2.34	0.70	4	1.47	0.6843

Two-way ANOVA results (normalized as described in Table 1) of dorsal root ganglia expression levels are shown with contrasts and associated p values and numbers of animals assayed per group. Bolded/italicized genes indicate specific contrast differences p < 0.05

* indicates difference trending to significance.

Abbreviations are as in Table 2.