Table 2. Genotype distributions of ETS-1 in RA patients and Controls in Chinese Han population.
SNPs | Model | Genotype | RA (n = 158) | Controls(n = 192) | OR(95%CI) | P value | ||
---|---|---|---|---|---|---|---|---|
N | % | N | % | |||||
rs73013527 | Dominant | CC | 87 | 55.1 | 66 | 34.4 | 1.00 | |
CT+TT | 71 | 44.9 | 126 | 65.6 | 0.43(0.28–0.66) | <0.001 | ||
Recessive | TT | 14 | 8.9 | 35 | 18.2 | 1.00 | ||
CC+CT | 144 | 91.1 | 157 | 81.8 | 0.44(0.23–0.84) | 0.012 | ||
Allele | C | 231 | 73.1 | 223 | 58.1 | 1.00 | ||
T | 85 | 26.9 | 161 | 41.9 | 0.51(0.37–0.70) | <0.001 | ||
rs4937333 | Dominant | CC | 53 | 33.5 | 61 | 31.8 | 1.00 | |
CT+TT | 105 | 66.5 | 131 | 68.2 | 0.92(0.59–1.45) | 0.725 | ||
Recessive | TT | 19 | 12.0 | 30 | 15.6 | 1.00 | ||
CC+CT | 139 | 88.0 | 162 | 84.4 | 0.74(0.40–1.37) | 0.334 | ||
Allele | C | 192 | 60.8 | 223 | 58.1 | 1.00 | ||
T | 124 | 39.2 | 161 | 41.9 | 0.90(0.66–1.21) | 0.472 | ||
rs11221332 | Dominant | CC | 140 | 88.6 | 166 | 86.5 | 1.00 | |
CT+TT | 18 | 11.4 | 26 | 13.5 | 0.82(0.43–1.56) | 0.546 | ||
Recessive | TT | 0 | 0.0 | 2 | 1.0 | - | ||
CC+CT | 158 | 100.0 | 190 | 99.0 | - | 0.503 | ||
Allele | C | 298 | 94.3 | 356 | 92.7 | 1.00 | ||
T | 18 | 5.7 | 28 | 7.3 | 0.77(0.42–1.42) | 0.397 |
Abbreviation: OR, odds ratio; CI, confidence interval.
Note: a) Data were presented as number and percentage for every group.
b) Significant p-values (<0.05) are highlighted in bold.