Table 3. Haplotype analysis of 3 ETS-1 polymorphisms in Chinese Han population.
Haplotype* | All(freq)** | Case(freq) | Control(freq) | OR(95%CI) | P value |
---|---|---|---|---|---|
CCC | 239.3(0.342) | 127.3(0.403) | 112.0(0.292) | 1.000 | |
TCC | 195.2(0.279) | 96.6(0.306) | 98.6(0.257) | 0.864(0.592–1.261) | 0.449 |
CCT | 139.8(0.200) | 51.2(0.162) | 88.6(0.231) | 0.505(0.329–0.775) | 0.002 |
TCT | 79.7(0.114) | 22.9(0.072) | 56.8(0.148) | 0.356(0.206–0.615) | <0.001 |
Abbreviation: OR, odds ratio; CI, confidence interval.
Note: a) Data were presented as number (percentage) for every group. A two-sided p value < 0.05 was considered as statistically significant.
b) * All frequencies <0.03 had been ignored in analysis. Loci chosen for hap-analysis were in this order: rs4937333, rs11221332, rs73013527.
c) **Data exhibited haplotype frequencies (percentage) in the whole 350 subjects.