Table 4. Association of ETS-1 polymorphisms with clinical characteristics in RA patients.
SNPs | Model | Genotype | DAS28 | RF(IU/L) | CRP(mg/L) | Anti-CCP(U/L) | ||||
---|---|---|---|---|---|---|---|---|---|---|
Md±IQR | P Value | Md±IQR | P Value | Md±IQR | P Value | Md±IQR | P Value | |||
rs73013527 | CC | 6.50±1.53 | 344.00±1527.45 | 11.05±38.67 | 307.15±398.05 | |||||
CT | 6.62±2.21 | 0.001 | 323.00±1123.8 | 0.821 | 18.70±55.53 | 0.028 | 371.40±257.45 | 0.351 | ||
TT | 7.81±1.01 | 465.00±939.5 | 49.5±42.68 | 369.80±235.82 | ||||||
Dominant | CC | 6.50±1.53 | 344.00±1527.45 | 11.05±38.67 | 307.15±398.05 | |||||
CT+TT | 6.80±1.84 | 0.162 | 366.00±1077.80 | 0.952 | 21.60±57.72 | 0.022 | 371.40±249.90 | 0.15 | ||
Recessive | TT | 7.81±1.01 | 465.00±939.5 | 49.5±42.68 | 369.80±235.82 | |||||
CC+CT | 6.54±1.62 | <0.001 | 342.00±1140.45 | 0.572 | 15.60±41.99 | 0.034 | 351.10±382.70 | 0.509 | ||
rs4937333 | CC | 6.67±1.69 | 342.00±1535.25 | 16.10±49.36 | 328.60±403.54 | |||||
CT | 6.52±1.98 | 0.127 | 310.00±923.55 | 0.313 | 18.50±44.75 | 0.983 | 363.40±376.00 | 0.777 | ||
TT | 6.71±1.66 | 635.00±1407.5 | 10.7±55.9 | 350.10±220.5 | ||||||
Dominant | CC | 6.67±1.69 | 342.00±1535.25 | 16.10±49.36 | 328.60±403.54 | |||||
CT+TT | 6.58±1.65 | 0.354 | 410.00±986.62 | 0.592 | 17.05±44.21 | 0.859 | 361.65±327.32 | 0.585 | ||
Recessive | TT | 6.71±1.66 | 635.00±1407.5 | 10.7±55.9 | 350.10±220.5 | |||||
CC+CT | 6.56±1.70 | 0.134 | 329.00±1129.12 | 0.216 | 17.65±46.32 | 0.926 | 361.65±383.3 | 0.559 | ||
rs11221332 | CC | 6.60±1.65 | 342.00±1188.85 | 16.7±47.32 | 340.10±379.7 | |||||
CT | 6.73±1.37 | 0.423 | 431.00±1015.2 | 0.874 | 17.20±48.73 | 0.860 | 416.65±242.5 | 0.262 | ||
Dominant | CC | 6.60±1.65 | 342.00±1188.85 | 16.7±47.32 | 340.10±379.7 | |||||
CT+TT | 6.73±1.37 | 0.423 | 431.00±1015.2 | 0.874 | 17.20±48.73 | 0.860 | 416.65±242.5 | 0.262 |
Abbreviation: Md±IQR: median±quartile interval.
Note: Significant p-values (<0.05) are highlighted in bold.