Table 3. Micro CT analysis of rapamycin-treated ΔTsc1 mice at 10 weeks of age.
Parameters | ΔTsc1 | ΔTsc1+RA | ΔTsc1+R A/ ΔTsc1 | P value |
---|---|---|---|---|
Cancellous bone | ||||
BMD[mg HA/ccm] | 660.81 ± 16.08 | 710.31 ± 4.47 | 1.1 | 0.017986 |
BV/TV[1] | 0.40 ± 0.04 | 0.26 ± 0.04 | 0.6 | 0.045705 |
Tb.N[1/mm] | 5.84 ± 0.16 | 6.21± 0.34 | 1.2 | 0.354591 |
Tb.Sp[mm] | 0.14 ± 0.01 | 0.28 ± 0.03 | 1.9 | 0.003653 |
Tb.Th[mm] | 0.096 ± 0.006 | 0.062 ± 0.004 | 0.6 | 0.001050 |
Cortical bone | ||||
BMD[mg HA/ccm] | 880.22 ± 10.76 | 947.25 ± 5.46 | 1.1 | 0.000536 |
Ct.Th[mm] | 0.417 ± 0.010 | 0.259 ± 0.027 | 0.7 | 0.000555 |
outer perimeter[mm] | 5.99 ± 0.16 | 4.95 ± 0.16 | 0.9 | 0.001926 |
inner perimeter[mm] | 3.33 ± 0.07 | 3.35 ± 0.05 | 1.0 | 0.780548 |
Values are shown as mean±SD (n = 5).