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. 2015 Jun 22;20(8):880–889. doi: 10.1634/theoncologist.2015-0020

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Figure 4. — Overall survival (OS) by hormone receptor status (positive vs. negative) and previous trastuzumab exposure in patients with HER2-positive metastatic breast cancer undergoing first-line trastuzumab-based therapy.

Abbreviations: HR+/Trast.+, patients with hormone receptor positive disease and previous trastuzumab exposure; HR+/Trast.−, patients with hormone receptor positive disease and without previous trastuzumab exposure; HR−/Trast.+, patients with hormone receptor-negative disease and previous trastuzumab exposure; HR−/Trast.−, patients with hormone receptor-negative disease and without previous trastuzumab exposure.