In the subset of neurons in which we assessed ZD alone and Recovery, SKF38393 (SKF) suppressed delay-related firing, and this suppression was blocked by a non-improving dose of ZD in monkeys performing the ODR task (N = 6). Firing increased during Recovery, following the removal of SKF.
A. Drug effects on the mean firing rate during the delay period. Error bars represent SEM. *p < 0.0005 vs. Control, ZD+SKF; †p = 0.030 vs. SKF.
B. Drug effects on population firing across all task epochs. The dotted line indicates onset of the fixation period, the dark grey background indicates the cue period, and the light grey background indicates the delay period.