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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Biol Psychiatry. 2015 Feb 4;78(12):860–870. doi: 10.1016/j.biopsych.2015.01.009

Figure 8.

Figure 8

The effects of SKF81297 (SKF) and stress on spatial working memory performance in rats.

A. SKF impaired spatial working memory performance in rats (N = 6) relative to vehicle (Veh) (*p = 0.010 vs. Veh+Veh), and this impairment was blocked by PFC infusions of ZD (†p=0.001 vs. SKF+Veh). Results represent % correct out of 10 trials. Error bars represent SEM.

B. The pharmacological stressor, FG7142 (FG) impaired spatial working memory performance in rats (N = 5) relative to vehicle (Veh) (*p = 0.004 vs. Veh+Veh), and this impairment was blocked by PFC infusions of ZD (†p = 0.006 vs. FG+Veh). Results represent % correct out of 10 trials. Error bars represent SEM.

C. FG impaired spatial working memory performance in rats (N = 7) relative to vehicle (Veh) (*p = 0.002 vs. Veh+Veh). However, this impairment was not blocked by ZD infusions dorsal to PFC (†p = 0.008 vs. Veh+Veh). Results represent % correct out of 10 trials. Error bars represent SEM.