Table 6.

Change in number of patients required for clinical effect size of 30% as a function of patient girth for neighborhood difference metrics.

	Small girth (850 mm)					Large girth (1200 mm)
	37 mm	28 mm	22 mm	17 mm		37 mm	28 mm	22 mm	17 mm
Coarseness	6	9	9	12	Coarseness	10	15	21	38
Contrast	13	15	34	38	Contrast	19	21	62	88
Busyness	10	11	7	27	Busyness	11	15	12	73
Complexity	11	11	16	14	Complexity	12	13	28	41
Strength	22	25	38	52	Strength	24	38	66	126