Table 4.

Calculated Ф values at 6, 12, and 18 h after administration

[Φ1B]
Drug	Dose (mg/time) (formulation)	6 h after administration (%)	12 h after administration (%)	18 h after administration (%)
Sumatriptan	3 (subcutaneous injection)	0	0	0
Zolmitriptan	2.5 (oral tablet)	76.3	36.1	3.3
Eletriptan	20 (oral tablet)	25.3	8.7	1.5
	40 (oral tablet)	52.9	25.7	11.4
	80 (oral tablet)	75.7	43.6	20.7
Rizatriptan	10 (oral tablet)	66.9	25.8	0
	10 (RPD oral tablet)	62.9	5.7	0
Naratritpan	1 (oral tablet)	54.3	32.1	10
	2.5 (oral tablet)	78.2	57.7	57.7
[Φ1D]
Drug	Dose (mg/time) (formulation)	6 h after administration (%)	12 h after administration (%)	18 h after administration (%)
Sumatriptan	3 (subcutaneous injection)	0	0	0
Zolmitriptan	2.5 (oral tablet)	90.7	63.1	33
Eletriptan	20 (oral tablet)	74.3	44.3	14.7
	40 (oral tablet)	90.7	75	50.7
	80 (oral tablet)	96.4	87.1	67.1
Rizatriptan	10 (oral tablet)	86.2	51.8	15
	10 (RPD oral tablet)	83.6	16.4	0
Naratritpan	1 (oral tablet)	54.3	30.3	11.4
	2.5 (oral tablet)	77.8	57	29.3

RPD rapid dissolution