Table 1.
Pathogenicity of the Japanese encephalitis vaccine strain in mice
| Mouse | LD50 | ||
|---|---|---|---|
| Suckling mouse S.C. |
3-week-old I.P. |
4-week-old I.C. |
|
| Anyang parent (4 × 107 pfu/mL) | 0.01 pfu | 80 pfu | 0.01 pfu |
| Anyang285a) (1 × 107 pfu/mL) | - | - | 9×103 pfu |
These results were originated from Kwon et al. [23].
S.C., subcutaneous; I.P., intraperitonial; I.C., intracerebral route; pfu, plaque forming unit.
a)The virus passage number in chicken primary embryo fibroblast cells.