Figure 4.

Chronic intermittent EtOH alters expression of select chromatin modifying enzymes in NAc but not PFC. Gene expression of a diverse set of chromatin modifying enzyme expression was assessed using RT-qPCR. (A) There was no significant effect of EtOH on expression of enzymes in the mPFC. (B) There was a significant effect of chronic EtOH exposure on gene expression (p < 0.05) and post-hoc analysis revealed significantly increased expression of Kat5 and Tet1 as well as a trend for increased expression of Kat2b. ^**p < 0.01, ^*p < 0.05, #p = 0.08, n = 4–5/group, data presented as mean ± SEM.