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Synaptic connectivity is not changed in Syt7 KO retina. A, RBCs and synaptic boutons were labeled with antibodies against PKCα and VGluT1, respectively. Similar synaptic layering patterns and overall morphology of RBCs were found between WT (top) and KO (bottom) mice. GCL, Ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; ONL, outer nuclear layer; OPL, outer plexiform layer. B, Syt1 was not upregulated in Syt7 KO mice. Scale bars, 20 μm.
