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. 2015 Jun 10;100(8):E1056–E1064. doi: 10.1210/jc.2014-4032

Table 3.

Logistic Regression for Selected CVD Risk Factors Compared With Those in the Referent Group (Low Density/Low Ratio)

Dependent Variable High Density/High Ratio
High Density/Low Ratio
Low Density/High Ratio
OR (95% CI) P OR (95% CI) P OR (95% CI) P
Women
    Low HDL
        MV 1.6 (1.1 to 2.2) .01 0.6 (0.4 to 0.9) .006 1.7 (1.2 to 2.3) .003
        MV + SAT 2.4 (1.7 to 3.6) <.0001 0.9 (0.6 to 1.4) .70 2.0 (1.4 to 2.8) <.0001
    High triglycerides
        MV 1.5 (1.1 to 2.1) .02 0.4 (0.2 to 0.6) <.0001 1.7 (1.2 to 2.3) .003
        MV + SAT 2.2 (1.5 to 3.5) <.0001 0.5 (0.3 to 0.9) .009 2.0 (1.4 to 2.8) .0001
    High glucose
        MV 1.2 (0.8 to 1.8) .40 0.3 (0.2 to 0.6) <.0001 1.6 (1.1 to 2.4) .008
        MV + SAT 1.9 (1.3 to 2.9) .003 0.6 (0.3 to 1.0) .04 2.1 (1.4 to 3.0) .0002
    Diabetes
        MV 6.7 (2.6 to 17.6) .0001 2.4 (0.8–6.9) .12 2.0 (0.7 to 5.6) .18
        MV + SAT 10.8 (4.1 to 29.0) <.0001 4.2 (1.4–12.5) .01 2.6 (0.9 to 7.2) .08
    Hypertension
        MV 1.6 (1.1 to 2.4) .009 0.6 (0.4 to 0.9) .01 1.8 (1.3 to 2.5) .001
        MV + SAT 2.5 (1.7 to 3.7) <.001 0.9 (0.6 to 1.4) .63 2.1 (1.5 to 3.1) <.0001
    CVD
        MV 3.9 (1.3 to 11.6) .02 0.8 (0.2 to 3.8) .82 2.9 (1.0 to 8.8) .06
        MV + SAT 3.4 (1.1 to 10.5) .03 0.7 (0.2 to 3.4) .68 2.8 (0.9 to 8.4) .07
    Metabolic syndrome
        MV 1.7 (1.2 to 2.4) .005 0.3 (0.2 to 0.5) <.0001 2.1 (1.5 to 3.0) <.0001
        MV + SAT 4.8 (3.1 to 7.4) <.0001 0.8 (0.4 to 1.3) .30 3.8 (2.6 to 5.6) <.0001
Men
    Low HDL
        MV 1.5 (1.1 to 2.0) .005 0.4 (0.3 to 0.6) <.0001 1.3 (0.9 to 1.7) .11
        MV + SAT 2.5 (1.8 to 3.5) <.0001 0.6 (0.4 to 0.9) .02 1.7 (1.2 to 2.4) .001
    High triglycerides
        MV 1.2 (0.9 to 1.5) .26 0.4 (0.3 to 0.6) <.0001 1.5 (1.2 to 2.0) .003
        MV + SAT 1.9 (1.4 to 2.7) <.0001 .6 (0.4 to 0.9) .005 2.0 (1.5 to 2.8) <.0001
    High glucose
        MV 0.7 (0.5 to 0.9) .003 0.5 (0.3 to 0.6) <.0001 1.1 (0.8 to 1.5) .47
        MV + SAT 1.0 (0.7 to 1.4) .98 0.6 (0.5 to 0.9) .009 1.4 (1.0 to 1.9) .03
    Diabetes
        MV 1.6 (0.9 to 2.6) .09 1.2 (0.7 to 2.2) .47 0.5 (0.2 to 1.0) .048
        MV + SAT 4.8 (2.6 to 9.2) <.0001 2.6 (1.4 to 4.9) .004 1.0 (0.5 to 2.0) .91
    Hypertension
        MV 0.8 (0.6 to 1.0) .08 0.4 (0.3 to 0.5) <.0001 0.8 (0.6 to 1.1) .13
        MV + SAT 1.5 (1.0 to 2.1) .03 0.6 (0.4 to 0.9) .01 1.1 (0.8 to 1.6) .48
    CVD
        MV 1.2 (0.7 to 2.0) .62 0.9 (0.5 to 1.7) .76 1.3 (0.7 to 2.3) .41
        MV + SAT 1.8 (0.9 to 3.5) .07 1.2 (0.6 to 2.5) .57 1.7 (0.9 to 3.1) .11
    Metabolic syndrome
        MV 0.6 (0.4 to 0.8) .0002 0.3 (0.2 to 0.4) <.0001 1.0 (0.8 to 1.4) .86
        MV + SAT 2.5 (1.7 to 3.6) <.0001 0.6 (0.4 to 0.9) .02 2.3 (1.7 to 3.2) <.0001

Estimates give differences in odds of the dependent variable in each group compared with the referent group (low SAT HU/low ratio). The multivariable (MV) model adjusts for age, current smoking status, alcohol use, physical activity, and hormone replacement therapy (models in women only). The MV + SAT model also adjusts for the absolute volume of SAT.