Table 1.
Baseline Demographic and Clinical Characteristics of Non-HIV and HIV-Infected Subjects
| Non-HIV-infected (n = 10) | HIV-infected (n = 20) | P Value | |
|---|---|---|---|
| Demographics | |||
| Age, y | 52 ± 2 | 49 ± 2 | .34 |
| Race, % | .27 | ||
| Caucasian | 80 | 45 | |
| African American | 20 | 35 | |
| Other | 0 | 20 | |
| Gender, % | .78 | ||
| Male | 70 | 65 | |
| HIV parameters | |||
| CD4+ T-cell count, cells/μL | N/A | 571 ± 73 | |
| Log HIV RNA viral load, copies/mL | N/A | 1.77 ± 0.19 | |
| Duration HIV, y | N/A | 18 ± 1 | |
| Duration ART use, y | N/A | 11 ± 1 | |
| Current PI use, % | N/A | 60 | |
| Current NRTI use, % | N/A | 90 | |
| Current NNRTI use, % | N/A | 25 | |
| History of HCV infection, % | 0 | 20 | .13 |
| Metabolic parameters | |||
| Waist circumference, cm | 89 ± 4 | 94 ± 3 | .40 |
| WHR | 0.90 ± 0.02 | 0.94 ± 0.02 | .15 |
| BMI, kg/m2 | 25 ± 1 | 26 ± 1 | .50 |
| VAT area, cm2 | 140 [84, 184] | 134 [56, 188] | .98 |
| SAT area, cm2 | 213 [122, 269] | 209 [107, 342] | .91 |
| SBP, mm Hg | 119 ± 3 | 115 ± 3 | .39 |
| DBP, mm Hg | 74 ± 3 | 73 ± 2 | .73 |
| Triglycerides, mg/dL | 88 [66, 155] | 105 [83, 149] | .45 |
| HDL cholesterol, mg/dL | 59 ± 6 | 52 ± 4 | .38 |
| Fasting glucose, mg/dL | 87 ± 1 | 84 ± 1 | .08 |
| Hemoglobin A1c, % | 5.5 [5.3, 5.7] | 5.4 [5.2, 5.6] | .23 |
| HOMA-IR | 0.59 [0.35, 1.59] | 0.98 [0.58, 1.85] | .21 |
| Creatinine, mg/dL | 0.79 ± 0.04 | 0.85 ± 0.03 | .27 |
| Potassium, mmol/L | 4.2 ± 0.1 | 4.1 ± 0.0 | .21 |
Abbreviations: DBP, diastolic BP; HCV, hepatitis C virus; HDL, high-density lipoprotein; N/A, not applicable; NNRTI, non-nucleoside reverse transcriptase inhibitors; NRTI, nucleoside/nucleotide reverse transcriptase inhibitors; PI, protease inhibitor; SBP, systolic BP; WHR, waist to hip ratio. Data are reported as mean ± SEM, percentage, or median [interquartile range].