Table 2.

Assessment of RAAS Activation

	Non-HIV-infected (n = 10)	HIV-infected (n = 20)	P Value
Metabolic parameters
MAP, mm Hg	85 ± 2	84 ± 1	.86
Sodium, mmol/L	137 ± 1	137 ± 0	.72
Creatinine, mg/dL	0.89 ± 0.06	0.92 ± 0.03	.58
Potassium, mmol/L	4.1 ± 0.1	4.1 ± 0.1	.56
Urine studies
Urine sodium, mmol per 24 h	18.2 ± 2.3	23.8 ± 4.5	.28
Urine potassium, mmol per 24 h	69.2 ± 6.5	68.4 ± 4.4	.92
Urine creatinine, mg per 24 h	1399 ± 122	1195 ± 71	.17
Urine cortisol, μg per 24 h	34.8 [17.2, 58.5]	30.4 [20.2, 42.2]	.52
RAAS parameters
PRA, ng/mL · h	1.80 [1.05, 3.18]	2.45 [1.43, 3.50]	.98
Ang II, pg/mL	30.0 [26.2, 36.3]	33.0 [26.1, 40.7]	.82
Serum aldosterone, ng/dL	9.2 [7.6, 13.6]	13.8 [9.7, 30.9]	.03
Urinary aldosterone excretion, ng per 24 h	34.1 [16.3, 42.0]	26.1 [18.4, 37.9]	.92

Data are reported as mean ± SEM or median [interquartile range]. Determinations were performed under conditions of equivalent low-sodium intake for both groups as described in the text.