Table 3.

Predictive Properties of First-Trimester Dysglycemia According to ADA, Endocrine Society (ES), and HbA1c Definitions Relative to Second-Trimester Gestational Diabetes Status

First-Trimester Criterion	Sensitivity	Specificity	Positive Predictive Value	Negative Predictive Value
ADA	0.23	0.95	0.60	0.81
ES	0.58	0.83	0.50	0.87
HbA1c	0.15	0.97	0.57	0.79
Composite (ES+HbA1c)a	0.62	0.82	0.50	0.88
Composite (ES+HbA1c+ADA)a	0.62	0.82	0.50	0.88

Note that HbA1c of 5.7%–6.4% are included in the ADA guidelines.

^aPositive on any of Endocrine Society or HbA1c criteria with or without ADA.