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. 2015 Aug 5;6:783. doi: 10.3389/fmicb.2015.00783

Table 3.

Influence of chalcones on MICFLC values determined for Candida albicans clinical isolates.

Compound MIC of FLC (μg/mL)a
B3 B4 Gu4 Gu5
1 16 4 256
5 1 4 4 256
6 1 16 4 32
11 0.5 1 2 128
15 1 8 4 64
18 1 2 4 32
19 1 8 4 256
20 1 16 4 128
21 1 2 4 64
22 1 16 4 128
23 1 8 4 128
25 1 8 4 128
VPb 1 0.5 4 64
TFPb 1 1 4 128
a

MIC values for FLC were determined by the serial dilution method as described Materials and Methods, in the presence of a fixed concentration of a compound tested (0.5 μg/mL for 11and 25 μg/mL for the other compounds).

b

Verapamil (50 μg/mL) and trifluoroperazine (20 μg/mL) were used as positive controls.

Cases of significant (>4-fold) MICFLC reduction by a given compound are highlighted in bold.