Fig. 7.

Representative immunoblot results and quantitative analysis of nitrotyrosine (A and B) and MnSOD (C and D) levels relative to β-actin in detrusor SM. Wild-type mice (WT), SM-specific Cre mice (Cre), and Sod2^lox/lox,SMCreER^T2(ki)^Cre/+ mice (KO) were treated with OHT at 8 wk of age. Later (12 wk), detrusor SM was harvested from 4 mice/group for immunoblot analyses. Bars with error bars represent means ± SE. *Significantly different from WT and KO groups at P < 0.0001. ^€Significantly different from KO group at P < 0.0001. #Significantly different from WT and Cre groups at P < 0.0001.