Table 2.
24-h Voiding Parameters |
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Groups | n | 24-h Fluid Consumed, ml | Voiding events | Mean void volume, ml/event | Total urine, ml |
Wild type | 9 | 33.0 ± 0.94 | 53 ± 3.12 | 0.49 ± 0.036 | 25.0 ± 0.91 |
SM-specific Cre | 6 | 28.5 ± 1.09 | 52 ± 5.16 | 0.45 ± 0.043 | 23.5 ± 0.83 |
SM-specific Sod2−/− | 13 | 31.2 ± 1.12 | 74 ± 4.70* | 0.37 ± 0.024# | 26.3 ± 1.17 |
Data are expressed as means ± SE; n, no. of mice. All mice were treated with OHT at 8 wk of age and assessed 12 wk after the final OHT injection.
Significantly higher than wild type (P = 0.006) and SM-specific Cre (P = 0.011).
Significantly lower than wild type (P = 0.026).