Table 3.

CMG parameters in wild-type, SM-specific Cre, and SM-specific Sod2^−/− mice

Parameter	Wild Type (n = 6)	SM-Specific Cre (n = 6)	SM-Specific Sod2−/− (n = 8)
Peak voiding pressure, cmH2O	31.81 ± 1.55	32.57 ± 1.53	36.95 ± 3.10
Functional bladder capacity, ml	0.24 ± 0.03	0.15 ± 0.01	0.13 ± 0.03*
Voiding volume, ml	0.12 ± 0.015	0.081 ± 0.009	0.070 ± 0.017
Residual volume, ml	0.11 ± 0.032	0.066 ± 0.020	0.049 ± 0.029
Compliance, ml/cmH2O	0.052 ± 0.013	0.039 ± 0.008	0.023 ± 0.009
Intercontraction interval, min	14.2 ± 1.93	8.77 ± 0.82	7.41 ± 2.04*

Data are expressed as means ± SE; n, no. of mice. CMG, cystometry. All mice were treated with OHT at 8 wk of age and assessed 12 wk after the final OHT injection.

^*Significantly lower than wild type (P < 0.05).