Table 4.

Area percentage of SM, collagen, and urothelium, as well as collagen:SM ratio of bladders of wild-type, SM-specific Cre, and SM-specific Sod2^−/− mice

Groups	SM, %	Collagen, %	Urothelium, %	Collagen-to-SM Ratio
Wild type	69.05 ± 2.95	22.38 ± 2.48	8.58 ± 1.30	0.33 ± 0.05
SM-specific Cre	65.90 ± 5.80	24.42 ± 4.42	9.70 ± 2.14	0.40 ± 0.09
SM-specific Sod2−/−	60.46 ± 1.90	27.18 ± 2.39	12.36 ± 1.29	0.46 ± 0.05

Data are expressed as means ± SE; n = 5 mice/group. All mice were treated with OHT at 8 wk of age and assessed 8 wk after the final OHT injection.