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LSS normalizes increased EMP production in endothelial cells with defective mitochondria. HUVECs were treated with antimycin A (AA; 10 μM) or LSS (20 dyne/cm2) for 12 h. Antimycin A-preconditioned HUVECs were subjected to STT or LSS (20 dyne/cm2) for succeeding 24 h. A: mitochondrial content. B: activated- (CD62E+) or total- (CD31+/CD42a−) EMP. Each column represents means ± SE from 3–5 independent experiments. *P < 0.05.
