Table 1.
Case/Model | T1/2, min* | Tlag, min | 103 R | AICc | w(AICc)† | ER‡ |
---|---|---|---|---|---|---|
1 (Fig. 1) | ||||||
PE | 79.6 ± 1.9 | 51.5 ± 0.8 | 8.3 ± 0.2 | −9,154 | 0.00006 | 1,750 |
GV | 77.3 ± 1.8 | 52.4 ± 0.8 | 8.5 ± 0.3 | −9,144 | <10−5 | >105 |
GVS | 97.4 ± 6.9 | 47.3 ± 1.0 | 6.6 ± 0.5 | −9,169 | 0.9994 | |
2 (Fig. 3) | ||||||
PE | 96.5 ± 2.5 | 64.9 ± 0.7 | 7.0 ± 0.3 | −8,962 | <10−9 | >109 |
GV | 90.3 ± 1.6 | 67.4 ± 0.7 | 8.0 ± 0.3 | −8,995 | <10−9 | >109 |
GVS | 84.8 ± 0.9 | 75.6 ± 1.2 | 8.8 ± 0.2 | −9,080 | 1.00000 | |
3 (Fig. 4) | ||||||
PE | 131 ± 6 | 76.5 ± 1.1 | 4.7 ± 0.3 | −8,389 | <10−9 | >109 |
GV | 121 ± 5 | 78.7 ± 1.1 | 5.3 ± 0.3 | −8,405 | <10−9 | >109 |
GVS | 104 ± 1 | 101 ± 2 | 7.0 ± 0.2 | −8,510 | 1.00000 | |
4 (Fig. 5) | ||||||
GVS | 153 ± 43 | 43.8 ± 1.4 | 4.2 ± 0.9 | −9,425 | <10−9 | >109 |
GVS2 | 109 ± 14 | 53.8 ± 1.0 | 7.2 ± 1.1 | −9,675 | 1.00000 | |
5 (Fig. 6) | ||||||
GVS | 105 ± 9 | 23.4 ± 0.5 | 6.3 ± 0.4 | −9,162 | <10−9 | >109 |
GVS2 | 54.2 ± 0.1 | 24.2 ± 0.5 | 13.6 ± 0.2 | −9,509 | 1.00000 | |
6 (Fig. 7) | ||||||
GVS | 127 ± 4 | 109 ± 4 | 4.4 ± 0.3 | −8,670 | <10−9 | >109 |
GVS2 | 109 ± 2 | 65.8 ± 1.4 | 6.5 ± 0.3 | −9,021 | 1.00000 | |
7 (Fig. 8) | ||||||
PE | 64.7 ± 1.0 | 40.8 ± 0.4 | 10.0 ± 0.2 | −9,567 | <10−8 | >108 |
GVS2 | 74 ± 10 | 52.8 ± 0.8 | 8.4 ± 0.8 | −9,605 | 1.00000 |
Values are means ± SD. T1/2, time to half emptying; Tlag, time to peak emptying; R, maximal rate; AICc, corrected Akaike Information Criterion; PE, power exponential model; GV, gamma variate model; GVS, gamma variate model with stretched exponential; GVS2, 2-component gamma variate model with stretched exponentials.
The values for parameters are best-fit values ± estimated SD by bootstrap method (see text).
w(AICc), Akaike weights; see Eq. 8.
ER, evidence ratios (based on Akaike weights) for a given model in favor of the most preferred model, which in cases 1–3 is GVS and in cases 4–7 is GVS2.