Effects of HNG on hepatic gene expression and activity of microsomal TG transfer protein (MTTP) in HFD mice. A: relative gene expression levels for sterol regulatory element-binding protein-1c (SREBP-1c), fatty acid synthase (Fasn), carnitine palmitoyl transferase-1a (CPT-1a), diglyceride acyltransferase 2 (DGAT2), phosphoenolpyruvate carboxykinase (PEPCK), apolipoprotein B (apoB), mttp, and hepatic lipase (HL) in SP- (open bars) or HNG-treated (gray bars) HFD mice (n = 6 each group). B and C: activity of hepatic (B) and intestinal (C) MTTP in HFD mice treated with SP or HNG for 4 wk. *P < 0.05; **P < 0.01.