Figure 1. Structures of PLCβ2 obtained in isolation (lower; PDB ID = 2ZKM)4 and GTP-bound Rac1 (upper; PDB ID = 2FJU)5 illustrating the auto-inhibitory model.
Rac1 switch1 is in green, switch 2 is in pink, and the X-Y linker is in red.
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