Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 28;6:7822. doi: 10.1038/ncomms8822

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) For more than 56% of the injected genes, phenotypes were observed. The pupal injection screen revealed phenotypes for a larger portion of genes compared with the larval injection screen. (b) Death of the injected animals was scored 22 days post injection (larval injection; blue circle) and 11 days post injection (pupal and larval injection; dark green and hatched blue circles). Note that embryonic lethality is based on maternal and zygotic gene knockdown. ‘Parental lethal': death of the injected animal. (c) Selected phenotypic categories after pupal injection. Embryonic lethal injections are further categorized showing that more than half of the embryonic lethal genes lead to abortion of embryogenesis before cuticle secretion. (d) Phenotypic categories after larval injection. ‘Defects during the process of metamorphosis': metamorphosis not completed or entered precociously. Insets: relations to the entire data set.