Figure 4. Ligand–receptor signalling network interface (hive view).
The results of a search for the CSF1–CSF1R ligand–receptor pair, filtered for the top cell-to-cell paths (ranked by the product of CSF1 and CSF1R expression). In this network, stimulated mast cells express the highest levels of CSF1 (1,109 TPM), while CD14+ derived endothelial progenitor cells express the highest levels of CSF1R (699 TPM). Users can select cells and/or ligand–receptor (LR) pairs of interest and filter edges and nodes based on expression levels of L and R. The interface is available at: http://fantom.gsc.riken.jp/5/suppl/Ramilowski_et_al_2015/.