Table 3. On-Target AUC, off-Target AUC, and DTI of Tylocrebrine.
| free drug | nontargeted nanoparticles | targeted nanoparticles | |
|---|---|---|---|
| AUCtumor (μg h mL–1) | 5.5 | 6.8 | 17.7 |
| AUCbrain (μg h mL–1) | 2.1 | 1.0 | 1.3 |
| DTI | 2.6 | 5.2 |
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