Table 4. Study 2: Circulating Ebola Virus Genomes in Primates Challenged with Ebola Virus 150 Days after Immunization with a Single Dose of AdCAGoptZGPa.
| animal no. | treatment/route | day 0 | day 3 | day 3.8 | day 14 | day 21 | day 28 |
|---|---|---|---|---|---|---|---|
| 0810091 | KPBS | –b | 880c | 1.84 × 105 | d | N.A.e | N.A. |
| 0805201 | KPBS | – | – | 7.79 × 105 | d | N.A. | N.A. |
| 0802197 | IN/IT | – | – | N.A. | – | – | – |
| 0809077 | IN/IT | – | – | N.A. | – | – | – |
| 0810003 | IN/IT | – | – | N.A. | – | – | – |
| 0805257 | SL | – | – | N.A. | d | N.A. | N.A. |
| 0804317 | SL | – | 1.74 × 104 | 9.84 × 106 | d | N.A. | N.A. |
| 0808233 | SL | – | 1.01 × 103 | 1.14 × 106 | d | N.A. | N.A. |
| 0809227 | PEI-SL | – | 2.08 × 104 | 1.57 × 104 | d | N.A. | N.A. |
| 0804819 | PEI-SL | – | – | 8.19 × 106 | d | N.A. | N.A. |
| 0807243 | PEI-SL | – | 3.33 × 104 | 3.3 × 105 | d | N.A. | N.A. |
a
Data were obtained by quantitative RT-PCR on RNA isolated from whole blood as described.
b
None detected. Sample fell below the detection limit of the assay (86 viral genomes/mL).
c
Units are genome copies per milliliter of whole blood (GC/mL).
d
Animal expired prior to sample collection at this time point.
e
Not assayed at this time point.