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Inter-related metabolic pathways for arginine and proline catabolism. The two amino acids are transported into the mitochondrion, where their catabolic routes converge to P5C formation. Abbreviations: GSA, glutamate semialdehyde; OAT, ornithine-δ-aminotransferase; P5C, δ1-pyrroline-5-carboxylate; P5CDH, P5C dehydrogenase; P5CR, P5C reductase; P5CS, P5C synthetase; ProDH, proline dehydrogenase; Q, ubiquinone.
