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. 2015 Jul 22;2015:204823. doi: 10.1155/2015/204823

Table 2.

All genes investigated in relation to canine DCM.

Gene Associated with DCM in humans Associated with canine DCM DCM dogs Control dogs Human reference Canine study reference
Number Breed
ACTC1 Y N 16 Doberman Pinscher 12 mixed breeds [39, 142] [77]
64 Irish Wolfhound 25 Irish Wolfhounds [143]
38 Newfoundland 36 Newfoundlands [69]
5 Doberman Pinscher 5 unspecified dogs without overt heart disease [144]
ACTN2 Y N 5 Doberman Pinscher 5 unspecified dogs without overt heart disease [39, 142] [144]
CAV1 N N 38 Newfoundland 36 Newfoundlands na [69]
CSRP3 Y N 64 Irish Wolfhound 25 Irish Wolfhounds [39, 142] [143]
38 Newfoundland 36 Newfoundlands [69]
5 Doberman Pinscher 2 Labradors [67]
5 Doberman Pinscher 5 unspecified dogs without overt heart disease [144]
DES Y N 25 Doberman Pinscher 10 Doberman Pinschers [39, 142] [35]
64 Irish Wolfhound 25 Irish Wolfhounds [143]
18 Doberman Pinscher 10 Doberman Pinschers [68]
38 Newfoundland 36 Newfoundlands [69]
DMD Y Y 2 German short-haired pointers 2 German short-haired pointers with reduced dystrophin [39, 142] [63]
LDB3 Y N 38 Newfoundland 36 Newfoundlands [39, 142] [69]
LMNA Y N 38 Newfoundland 36 Newfoundlands [39, 142] [69]
5 Doberman Pinscher 2 Labradors [67]
MYBPC3 Y N 5 Doberman Pinscher 5 unspecified dogs without overt heart disease [39, 142] [144]
MYH7 Y N 38 Newfoundland 36 Newfoundlands [39, 142] [69]
5 Doberman Pinscher 2 Labradors [67]
5 Doberman Pinscher 5 unspecified dogs without overt heart disease [144]
PDK4 N Y 66 Doberman Pinscher 66 Doberman Pinschers + 100 others from 11 breeds na [60]
PLN Y N 25 Doberman Pinscher 10 Doberman Pinschers [39, 142] [35]
2 Doberman Pinscher,
2 Newfoundland, 2 great dane		 computer database only [66]
64 Irish Wolfhound 25 Irish Wolfhounds [143]
38 Newfoundland 36 Newfoundlands [69]
SGCD Y N 25 Doberman Pinscher 10 Doberman Pinschers [39, 142] [35]
64 Irish Wolfhound 25 Irish Wolfhounds [143]
38 Newfoundland 36 Newfoundlands [69]
25 Doberman Pinscher 13 Doberman Pinschers [145]
STRN N Y 33 Boxer 16 Boxers na [62]
TAZ Y N 64 Irish Wolfhound 25 Irish Wolfhounds [39] [143]
TCAP Y N 8 Irish Wolfhound 5 Irish Wolfhounds [39, 142] [146]
38 Newfoundland 36 Newfoundlands [69]
5 Doberman Pinscher 5 unspecified dogs without overt heart disease [144]
TMOD N N 64 Irish Wolfhound 25 Irish Wolfhounds na [143]
TNNC1 Y N 5 Doberman Pinscher 2 Labradors [39, 142] [67]
TNNI3 Y N 38 Newfoundland 36 Newfoundlands [39, 142] [69]
TNNT2 Y N 5 Doberman Pinscher 2 Labradors [39, 142] [67]
5 Doberman Pinscher 5 dogs without overt heart disease [144]
38 Newfoundland 36 Newfoundlands [69]
TPM1 Y N 38 Newfoundland 36 Newfoundlands [39] [69]
5 Doberman Pinscher 5 dogs without overt heart disease [144]
TTN Y N 38 Newfoundland 36 Newfoundlands [39, 142] [69]
2 Doberman Pinscher 5 mixed breeds [147]
VCL Y N 5 Doberman Pinscher 5 dogs without overt heart disease [39, 142] [144]
38 Newfoundland 36 Newfoundlands [69]

Y = yes, N = no.