Skip to main content
. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Pharmacoepidemiol Drug Saf. 2014 Sep 29;23(11):1147–1153. doi: 10.1002/pds.3717

Table 2.

multivariable analysis among the current digoxin users, looking at five different levels of first prescription timing before index date

First digoxin
treatment before
index date		 Cases
(20,990)
N (%)		 Controls
(82,054)
N (%)		 Unadjusted OR
(95% CI, p-Value)		 Adjusted OR1
(95% CI, p-Value)
No digoxin Rx. 20,147 (96.0%) 79,936 (97.4%) Ref. Ref.
<6 months 110 (0.5%) 190 (0.2%) 2.36 (1.86–2.99, <0.0001) 2.28 (1.80–2.90, <0.0001)
6 months – <1 year 103 (0.5%) 238 (0.3%) 1.77 (1.40–2.24, <0.0001) 1.64 (1.30–2.08, <0.0001)
1– <5 years 403 (1.9%) 1,083 (1.3%) 1.49 (1.32–1.67, <0.0001) 1.41 (1.25–1.59, <0.0001)
5– <10 years 181 (0.9%) 480 (0.6%) 1.50 (1.26–1.78, <0.0001) 1.45 (1.22–1.72, <0.0001)
>10 years 46 (0.2%) 127 (0.2%) 1.47 (1.05–2.07, =0.027) 1.41 (1.00–1.99, =0.049)
1

Adjusted to diabetes mellitus, BMI, smoking history, alcohol consumption, chronic use of Aspirin/NSAIDs, and performance of screening colonoscopy.