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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Pharmacoepidemiol Drug Saf. 2014 Sep 29;23(11):1147–1153. doi: 10.1002/pds.3717

Table 3.

multivariable analysis among the former digoxin users, looking at five different levels of first prescription timing before index date

First digoxin
treatment before
index date		 Cases
(20,990)
N (%)		 Controls
(82,054)
N (%)		 Unadjusted OR
(95% CI, p-Value)		 Adjusted OR1
(95% CI, p-Value)
No digoxin Rx. 20,147 (96.0%) 79,936 (97.4%) Ref. Ref.
1– <5 years 83 (0.4%) 302 (0.4%) 1.08 (0.85–1.39, =0.52) 1.06 (0.83–1.35, =0.66)
5– <10 years 64 (0.3%) 210 (0.2%) 1.25 (0.94–1.65, =0.13) 1.21 (0.91–1.61, =0.18)
>10 years 14 (0.1%) 73 (0.1%) 0.76 (0.43–1.36, =0.36) 0.73 (0.41–1.30, =0.29)
1

Adjusted to diabetes mellitus, BMI, smoking history, alcohol consumption, chronic use of Aspirin/NSAIDs, and performance of screening colonoscopy.