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. 2004 Jul;17(3):638–680. doi: 10.1128/CMR.17.3.638-680.2004

TABLE 4.

Fungal colonization in VLBW and ELBW infantsa

Characteristic Results for study (study period)
Baley et al. (30) (1983) Hageman et al. (183) (1985) Pappu-Katikaneni et al. (362) (1991) Rowen et al. (395) (1992) Saiman et al. (402) (1993-1995) Huang et al. (215) (1996) Kicklighter et al. (255) (1998-1999)b Kaufman et al. (246) (1998-2000)b
Birth wt (gr) <1,500 <1,500 <1,500 <1,500 <1,500 <1,500 <1,500 <1,000
No. of patients 146 38 40 116 780 116 52b 50b
% of patients with colonization 27 47 63 34 31 22 46 60
% of patients colonized with:
    C. albicans 16 24 40 26 18 13 44 44
    C. papapsilosis 5 24 10 4 13 6 37 45
    C. glabrata 0 0 0 3 <1 4 3
    C. guilliermondii 0 0 0 0 <1 0 3
    C. lusitaniae 0 0 0 0 0 11.1 5.1
    C. tropicalis 2.1 0 2.5 1.7 0 3.7 0
Other 3.4 0 0 0 2.7c 0.8 0 1.1
% of total no. of patients colonized by site:
    Skin
        Groin or axilla 13.7 12.9 0 48
        Umbilicus 8
    Gastrointestinal tract
        Rectal 19.2 33.6 31 12.9 45 54
        Stool 62.5
    Respiratory tract
        Oropharyngeal 11 11.2d 6
        Endotracheal 4.8 11.2d 2.6 42
    Urine 8.3 7.7
% of total no. of patients with fungal sepsis 2.1 7.9 12.5 6.0 3.1 2.6 3.9 16
a

Summary of eight studies (30, 183, 215, 246, 255, 362, 395, 402).

b

Analysis of the control patients in these randomized trials.

c

Includes non-albicans and non-parapsilosis species.

d

Nasopharyngeal and endotracheal cultures did not correlate with one another.