TABLE 4.
Fungal colonization in VLBW and ELBW infantsa
Characteristic | Results for study (study period)
|
|||||||
---|---|---|---|---|---|---|---|---|
Baley et al. (30) (1983) | Hageman et al. (183) (1985) | Pappu-Katikaneni et al. (362) (1991) | Rowen et al. (395) (1992) | Saiman et al. (402) (1993-1995) | Huang et al. (215) (1996) | Kicklighter et al. (255) (1998-1999)b | Kaufman et al. (246) (1998-2000)b | |
Birth wt (gr) | <1,500 | <1,500 | <1,500 | <1,500 | <1,500 | <1,500 | <1,500 | <1,000 |
No. of patients | 146 | 38 | 40 | 116 | 780 | 116 | 52b | 50b |
% of patients with colonization | 27 | 47 | 63 | 34 | 31 | 22 | 46 | 60 |
% of patients colonized with: | ||||||||
C. albicans | 16 | 24 | 40 | 26 | 18 | 13 | 44 | 44 |
C. papapsilosis | 5 | 24 | 10 | 4 | 13 | 6 | 37 | 45 |
C. glabrata | 0 | 0 | 0 | 3 | <1 | 4 | 3 | |
C. guilliermondii | 0 | 0 | 0 | 0 | <1 | 0 | 3 | |
C. lusitaniae | 0 | 0 | 0 | 0 | 0 | 11.1 | 5.1 | |
C. tropicalis | 2.1 | 0 | 2.5 | 1.7 | 0 | 3.7 | 0 | |
Other | 3.4 | 0 | 0 | 0 | 2.7c | 0.8 | 0 | 1.1 |
% of total no. of patients colonized by site: | ||||||||
Skin | ||||||||
Groin or axilla | 13.7 | 12.9 | 0 | 48 | ||||
Umbilicus | 8 | |||||||
Gastrointestinal tract | ||||||||
Rectal | 19.2 | 33.6 | 31 | 12.9 | 45 | 54 | ||
Stool | 62.5 | |||||||
Respiratory tract | ||||||||
Oropharyngeal | 11 | 11.2d | 6 | |||||
Endotracheal | 4.8 | 11.2d | 2.6 | 42 | ||||
Urine | 8.3 | 7.7 | ||||||
% of total no. of patients with fungal sepsis | 2.1 | 7.9 | 12.5 | 6.0 | 3.1 | 2.6 | 3.9 | 16 |