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. 2004 Jul;17(3):638–680. doi: 10.1128/CMR.17.3.638-680.2004

TABLE 5.

Comparison of C. albicans, C. parapsilosis, and C. glabrata sepsisa

Characteristic Results for:
P value
C. albicans C. parapsilosis C. glabrata
Baseline characteristics
    No. of patients 41 8 9
    Gestational age (wk) 26.6 ± 0.5 27.3 ± 1.3 29.7 ± 1.2 0.01
    Birth wt (g) 932 ± 75 965 ± 194 1,442 ± 292 0.02
    No. (%) of VLBW (<1,500 g) infants 38 (93) 7 (88) 7 (78) NS
    No. (%) born via vaginal delivery 26 (63) 4 (50) 7 (78) NS
Factors present at the diagnosis of fungemia
    Age at diagnosis (days) 17 (11-31) 25 (17-87) 14 (10-21) NS
    No. (%) on antibiotics 12 (38) 3 (38) 6 (67) NS
    No. (%) with apnea 28 (68) 4 (50) 2 (22) 0.01
    Lowest platelet count (103/mm3) 74 ± 9 39 ± 2 124 ± 34 0.04
    No. of positive blood cultures for fungus 2.1 ± 1.1 1.8 ± 0.71 2.0 ± 1.3 NS
    No. (%) with candiduria 15 (37) 2 (25) 2 (22) NS
    No. (%) with meningitis 5 (12) 1 (13) 1 (11) NS
    No. with renal abscessc/total no. tested (%) 5/38 (13) 1/7 (14) 0/7 (0) NS
    No. with cardiac vegetations/total no. tested (%) 2/30 (7) 0/6 (0) 0/8 (0) NS
    No. (%) with necrotizing enterocolitis 6 (15) 0 1 (11) NS
    No. (%) dying of Candida infection 0 0 0 NS
    No. (%) who died, all-cause mortality 3 (7) 0 0 NS
a

Data from reference 131. Plus-minus values are mean ± standard deviation. Median is given as 25th to 75th percentile.

b

Significant difference between glabrata and non-glabrata groups (P < 0.05). NS, not significant.

c

Urinary tract ultrasound and echocardiogram were not performed on every patient.