TABLE 5.
Characteristic | Results for:
|
P value | ||
---|---|---|---|---|
C. albicans | C. parapsilosis | C. glabrata | ||
Baseline characteristics | ||||
No. of patients | 41 | 8 | 9 | |
Gestational age (wk) | 26.6 ± 0.5 | 27.3 ± 1.3 | 29.7 ± 1.2 | 0.01 |
Birth wt (g) | 932 ± 75 | 965 ± 194 | 1,442 ± 292 | 0.02 |
No. (%) of VLBW (<1,500 g) infants | 38 (93) | 7 (88) | 7 (78) | NS |
No. (%) born via vaginal delivery | 26 (63) | 4 (50) | 7 (78) | NS |
Factors present at the diagnosis of fungemia | ||||
Age at diagnosis (days) | 17 (11-31) | 25 (17-87) | 14 (10-21) | NS |
No. (%) on antibiotics | 12 (38) | 3 (38) | 6 (67) | NS |
No. (%) with apnea | 28 (68) | 4 (50) | 2 (22) | 0.01 |
Lowest platelet count (103/mm3) | 74 ± 9 | 39 ± 2 | 124 ± 34 | 0.04 |
No. of positive blood cultures for fungus | 2.1 ± 1.1 | 1.8 ± 0.71 | 2.0 ± 1.3 | NS |
No. (%) with candiduria | 15 (37) | 2 (25) | 2 (22) | NS |
No. (%) with meningitis | 5 (12) | 1 (13) | 1 (11) | NS |
No. with renal abscessc/total no. tested (%) | 5/38 (13) | 1/7 (14) | 0/7 (0) | NS |
No. with cardiac vegetations/total no. tested (%) | 2/30 (7) | 0/6 (0) | 0/8 (0) | NS |
No. (%) with necrotizing enterocolitis | 6 (15) | 0 | 1 (11) | NS |
No. (%) dying of Candida infection | 0 | 0 | 0 | NS |
No. (%) who died, all-cause mortality | 3 (7) | 0 | 0 | NS |
Data from reference 131. Plus-minus values are mean ± standard deviation. Median is given as 25th to 75th percentile.
Significant difference between glabrata and non-glabrata groups (P < 0.05). NS, not significant.
Urinary tract ultrasound and echocardiogram were not performed on every patient.