Table 1.

Characteristics of Intravascular Glucose Monitoring Systems.

System, company	Detection technology	Sampling site	Measurement site	Regulatory status	System status	Technical issues
GlucoScout, Via Medical	Electrochemical, glucose oxidase	Peripheral venous	Ex vivo	FDA 510(k) cleared	On market, EEA and US	Unheparinized glucose-containing infusion volume
GlucoClear, Edwards LifeSciences	Dexcom electrochemical, glucose oxidase	Peripheral venous	Ex vivo	CE Mark	On market, EEA	Corporate support?
Automated blood glucose monitor, Luminous Medical	Near-infrared; then electrochemical glucose oxidase	Peripheral venous, arterial	Ex vivo	None	Company closed	Regulatory approval; detection technology
OptiScanner 5000, OptiScan Biomedical	Mid-infrared, plasma	CVC, peripheral venous	Ex vivo	CE mark	On market, EEA	Unheparinized infusion, drug interferences?
OPTImus, IntelliDX	Electrochemical	Peripheral venous	Ex vivo	None	Company closed	Funding?
GlySure CGMS, GlySure	Boronate fluorescence	CVC	In vivo	CE Mark	In development	Nonthrombic sensor; interferences?
Glucath, Glumetrics	Boronate-quenched fluorescence	Peripheral venous, arterial	In vivo	None	Company closed	Thrombus formation
Glucoset, (originally Invivosense)	Boronate optomechanical	Peripheral venous	In vivo	None	Under development	Interferences?
Autosampler, Cascade Metrix	Electrochemical	Peripheral venous	Ex vivo	None	Under development	Development progress?